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BioKin, Ltd.

www.biokin.com/index.html
About Us

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Program DynaFit
Analysis of (bio)chemical kinetics and equilibria
www.biokin.com/dynafit/index.html
DynaFit Manual
Documentation for program DynaFit
www.biokin.com/dynafit/manual.html
Download DynaFit
Download the program DynaFit for the analysis of (bio)chemical kinetics and equilibria
www.biokin.com/dynafit/download.html
DynaFit under Linux Mint
Instructions to install and test DynaFit under Linux Mint 16
www.biokin.com/dynafit/linuxmint.html
Bibliography
Research papers in which DynaFit was used for the analysis of experimental data.
www.biokin.com/dynafit/bibliography.html

DynaFit License
Request a DynaFit license
www.biokin.com/dynafit/license/index.html
Request Academic License
For DynaFit users affilitated with educational organizations only
www.biokin.com/dynafit/license/academic.html
Request Commercial License
For DynaFit users affilitated with for-profit organizations
www.biokin.com/dynafit/license/commercial.html

Consulting Services
Data analysis in chemistry, biology, biochemistry, and related fields
www.biokin.com/consulting/index.html
Sample Contract #1
Consulting and custom software development
www.biokin.com/consulting/sample1.html
Sample Contract #2
Consulting and custom software development
www.biokin.com/consulting/sample2.html
Sample Contract #3
Consulting and custom software development
www.biokin.com/consulting/sample3.html
Sample Contractor Agreement
Consulting and custom software development
www.biokin.com/consulting/sample4.html

BioKin Publications
Journal articles and technical reports
www.biokin.com/publications/index.html
Journal Articles
Journal articles and book chapters
www.biokin.com/publications/articles.html
Technical Reports
Longer or highly focussed research reports
www.biokin.com/publications/techreports.html

Technical Notes
Shorter notes on technical subjects
www.biokin.com/publications/technotes/index.html
History of the "Morrison Equation"
History, variants and usage of the "Morrison equation" in enzyme inhibition kinetics
www.biokin.com/publications/technotes/TN201501.html
EGFR inhibition: Ki and kinact
Determination of inhibition constants (Ki) and inactivation rate constants (kinact)
www.biokin.com/publications/technotes/TN201502.html
King-Altman method in DynaFit
DynaFit was updated to derive "kinetic constants" (Michaelis constants etc.)
www.biokin.com/publications/technotes/TN201503.html
An algebraic model for covalent inhibition kinetics
Preprint
www.biokin.com/publications/technotes/TN201504.html
Substrate kinetics from reaction progress
DynaFit tutorial
www.biokin.com/publications/technotes/TN201505.html
Time-dependent inhibition of 5alpha-steroid reductase
DynaFit tutorial
www.biokin.com/publications/technotes/TN201506.html
Integrated Michaelis-Menten equation in DynaFit. Part 1.
Determination of substrate kinetic parameters of EGFR kinase
www.biokin.com/publications/technotes/TN201601.html
Integrated Michaelis-Menten equation in DynaFit. Part 2.
Determination of substrate kinetic parameters of 5alpha-ketosteroid reductase
www.biokin.com/publications/technotes/TN201602.html
Integrated Michaelis-Menten equation in DynaFit. Part 3.
Determination of substrate kinetic parameters of HIV protease
www.biokin.com/publications/technotes/TN201603.html

Lectures and Seminars

www.biokin.com/lectures.html

Lecture Courses and Workshops
www.biokin.com/courses/index.html

Brno 2014: Binding and Kinetics for Experimental Biologists
Masaryk University | Department of Experimental Biology | May, 12-16 2014
www.biokin.com/courses/BKEB/index.html
Course Syllabus
Organization details
www.biokin.com/courses/BKEB/syllabus.html
Course Lectures
Copies of PowerPoint slides
www.biokin.com/courses/BKEB/lectures.html

London 2014: Binding Constants and Mechanisms
Biochemical Society (U.K.) | May 2, 2014
www.biokin.com/courses/london2014/index.html
Training Day Organisation
Monday - May 2, 2014
www.biokin.com/courses/london2014/organisation.html
Training Day Lectures
Copies of PowerPoint slides
www.biokin.com/courses/london2014/lectures.html
Preloaded Software Package
Download DynaFit with a 30-day license for Training Day delegates
www.biokin.com/courses/london2014/software.html

Tools
Basic tools for statistical data analysis: standard deviation, F-statistics, and more.
www.biokin.com/tools/index.html
Optimal Design of Experiments
For dose-response inhibitor screening
www.biokin.com/tools/design.html
Average and Standard Deviation
Including Student t confidence intervals
www.biokin.com/tools/average.html
Critical values of F-Statistics
An on-line statistical calculator
www.biokin.com/tools/f-critical.html
Nested models
Statistical calculator for model discrimination analysis
www.biokin.com/tools/nestedmodels.html
Two treatment groups
Statistical calculator for the difference in two treatment groups
www.biokin.com/tools/twogroups.html
Kinetics with MAPLE
Generate MAPLE code for deriving simple rate laws
www.biokin.com/tools/maplekin.html
Kinetics with Mathematica
Generate Mathematica code for deriving simple rate laws
www.biokin.com/tools/mathekin.html

King-Altman Method
Analysis of steady-state enzyme kinetics
www.biokin.com/tools/king-altman/index.html
Submit Data
Derivation of steady-state rate equations using the King-Altman method
www.biokin.com/tools/king-altman/submit.html
Example Problems
Derivation of steady-state rate equations using the King-Altman method
www.biokin.com/tools/king-altman/examples.html
Theoretical Notes
Derivation of steady-state rate equations using the King-Altman method
www.biokin.com/tools/king-altman/theory.html

Enzyme Inhibitor Potency
Grouping of enzyme inhibitors into tiers of (nearly) identical potency
www.biokin.com/tools/potency/index.html
Submit Data
Grouping of enzyme inhibitors into tiers of (nearly) identical potency
www.biokin.com/tools/potency/submit.html
Example Problems
Grouping of enzyme inhibitors into tiers of (nearly) identical potency
www.biokin.com/tools/potency/examples.html
Theoretical Notes
Grouping of enzyme inhibitors into tiers of (nearly) identical potency
www.biokin.com/tools/potency/theory.html

Site map
A listing of all files that comprise this web site.
www.biokin.com/sitemap.html
Contact Information
Contact information for BioKin Ltd.
www.biokin.com/contact.html

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Thu May 16 16:21:32 2024